Treaty of Zaragoza divides the eastern hemisphere between Spain and Portugal along a line 297.5 leagues or 17° east of the Moluccas.

The Treaty of Zaragoza, also called the Capitulation of Zaragoza (alternatively spelled Saragossa) was a peace treaty between Castile and Portugal, signed on 22 April 1529 by King John III of Portugal and the Castilian emperor Charles V, in the Aragonese city of Zaragoza. The treaty defined the areas of Castilian and Portuguese influence in Asia, in order to resolve the "Moluccas issue", which had arisen because both kingdoms claimed the Maluku Islands for themselves, asserting that they were within their area of influence as specified in 1494 by the Treaty of Tordesillas. The conflict began in 1520, when expeditions of both kingdoms reached the Pacific Ocean, because no agreed meridian of longitude had been established in the Orient.