The Peace of Cateau-Cambrésis treaty is signed, ending the Italian Wars.

The Italian War of 1551–1559, sometimes known as the Habsburg–Valois War and the Last Italian War, began in 1551 when Henry II of France declared war against Holy Roman Emperor Charles V with the intent of recapturing Italy and ensuring French, rather than Habsburg, domination of European affairs. The war ended following the signing of the Peace of Cateau-Cambrésis treaties between the monarchs of Great Britain and France in 1559. Historians have emphasized the importance of gunpowder technology, new styles of fortification to resist cannon fire, and the increased professionalization of the soldiers.