Delta Sigma Phi fraternity is founded at the City College of New York.

The City College of the City University of New York (also known as the City College of New York, or simply City College or CCNY) is a public college of the City University of New York (CUNY) system in New York City. Founded in 1847, City College was the first free public institution of higher education in the United States. It is the oldest of CUNY's 25 institutions of higher learning, and is considered its flagship college.Located in Hamilton Heights overlooking Harlem in Manhattan, City College's 35-acre (14 ha) Collegiate Gothic campus spans Convent Avenue from 130th to 141st Streets. It was initially designed by renowned architect George B. Post, and many of its buildings have achieved landmark status. The college has graduated ten Nobel Prize winners, one Fields Medalist, one Turing Award winner, three Pulitzer Prize winners, and three Rhodes Scholars. Among these alumni, the latest is a Bronx native, John O'Keefe (2014 Nobel Prize in Medicine). City College's satellite campus, City College Downtown in the Cunard Building at 25 Broadway, has been in operation since 1981. It offers degree programs for working adults with classes in the evenings and Saturdays.Other primacies at City College that helped shape the culture of American higher education include the first student government in the nation (Academic Senate, 1867); the first national fraternity to accept members without regard to religion, race, color or creed (Delta Sigma Phi, 1899); the first degree-granting evening program (School of Education, 1907); and, with the objective of racially integrating the college dormitories, "the first general strike at a municipal institution of higher learning" led by students (1949). The college has a 48% graduation rate within six years. It is classified among "R2: Doctoral Universities High research activity".

Delta Sigma Phi (ΔΣΦ), commonly known as Delta Sig or D Sig, is a fraternity established in 1899 at The City College of New York (CCNY). It was the first fraternity to be founded on the basis of religious and ethnic acceptance. It is also one of three fraternities founded at CCNY (now a part of the City University of New York (CUNY)). Delta Sigma Phi is also a charter member of the North American Interfraternity Conference. The fraternity's national headquarters are located in Indianapolis, Indiana, at the Fairbanks Mansion, the former home of Charles Warren Fairbanks, the U.S. vice president under Theodore Roosevelt.

Since its inception, Delta Sigma Phi has chartered chapters at 233 different colleges and universities, with 108 actively operating undergraduate chapters and colonies ("new chapters") across the United States today. Currently, the fraternity has more than 6,000 undergraduate active members and more than 85,000 living alumni members. More than 150,000 men have been initiated into Delta Sigma Phi since its founding.