A strong earthquake strikes the South Alpine region of Friuli in modern Italy, causing considerable damage to buildings as far away as Rome.

The 1348 Friuli earthquake, centered in the South Alpine region of Friuli, was felt across Europe on 25 January. The earthquake hit in the same year that the Great Plague ravaged Italy. According to contemporary sources, it caused considerable damage to structures; churches and houses collapsed, villages were destroyed and foul odors emanated from the earth.