The Six-Day War in Kisangani begins in Kisangani, in the Democratic Republic of the Congo, between Ugandan and Rwandan forces. A large part of the city is destroyed.

The Six-Day War (French: Guerre des Six Jours) was a series of armed confrontations between Ugandan and Rwandan forces around the city of Kisangani in the Democratic Republic of the Congo from 5 to 10 June 2000. The war formed part of the wider Second Congo War (1998–2003).

Kisangani was also a scene of violence between Rwandan and Ugandan troops in August 1999 and 5 May 2000. However, the conflicts of June 2000 were the most lethal and seriously damaged a large part of the city, with more than 6,600 rounds fired.According to Justice et Libération, a human rights organisation based in Kisangani, the violence resulted in around 1,000 deaths and wounded at least 3,000, the majority of whom were civilians.