Kerry Wood strikes out 20 Houston Astros to tie the major league record held by Roger Clemens. He threw a one-hitter and did not walk a batter in his fifth career start.

The Houston Astros are an American professional baseball team based in Houston. The Astros compete in Major League Baseball (MLB) as a member club of the American League (AL) West division, having moved to the division in 2013 after spending their first 51 seasons in the National League (NL).The Astros were established as the Houston Colt .45s and entered the National League as an expansion team in 1962 along with the New York Mets. The current name, reflecting Houston's role as the host of the Johnson Space Center, was adopted three years later, when they moved into the Astrodome, the first domed sports stadium and the so-called "Eighth Wonder of the World." The Astros moved to a new stadium called Minute Maid Park in 2000. The Astros played in the NL West division from 1969 to 1993, then the NL Central division from 1994 to 2012, before being moved to the AL West as part of a minor realignment in 2013.

The Astros posted their first winning record in 1972 and made the playoffs for the first time in 1980. The Astros made their first World Series appearance in 2005 but were swept by the ALs Chicago White Sox. In the following decade, the team embraced sabermetrics and pioneered new analytical technologies during the early 2010s, transforming from a middling franchise into one of MLB's most dominant and successful clubs, winning over 100 games in three straight seasons, although they were central players in a major cheating scandal. The Astros won the 2017 World Series, their first championship, against the Los Angeles Dodgers in seven games in the wake of Hurricane Harvey. Having been defeated by Boston the following year in the 2018 ALCS, the Astros returned to the World Series in 2019, losing to the Washington Nationals in seven games despite putting together an all-time great, and franchise-best, regular season.

On January 13, 2020, Astros manager A. J. Hinch and general manager Jeff Luhnow were suspended by MLB for one year after an investigation confirmed sign stealing by the Astros during their 2017 World Series campaign; both men were fired shortly thereafter. Dusty Baker was announced as the new manager, and James Click as the new general manager, on January 29 and February 3, 2020, respectively. During the pandemic-shortened 2020 season, the Astros again qualified for the playoffs (this time with a losing record), making a run for their fourth consecutive American League Championship Series appearance after having beaten the Minnesota Twins and division rival Oakland Athletics. However, despite becoming just the second team in the history of baseball to rebound from an 03 series deficit, the Astros ultimately fell to the Tampa Bay Rays after seven historically tight games in the ALCS. In 2021, the Astros won the American League West title for the fourth time in five seasons while winning 95 games. Then, in the 2021 American League Championship Series, they beat the Boston Red Sox in six games to go to their third World Series in five seasons, a pennant win-rate not seen in nearly a decade. There, they lost to the Atlanta Braves in six games.

From 1962 through the end of the 2021 season, the Astros' all-time record is 4,725-4,764 (.498)

Kerry Lee Wood (born June 16, 1977) is an American former baseball pitcher who played 14 seasons in Major League Baseball (MLB) for the Chicago Cubs, Cleveland Indians, and New York Yankees.

Wood first came to prominence as a 20-year-old rookie when he recorded 20 strikeouts in a one-hit shutout against the Houston Astros, which some have argued may be the greatest single-game pitching performance in MLB history. The game also made Wood the co-holder of the MLB record for strikeouts in a single game (20) and earned Wood the nickname Kid K. He was later named the 1998 National League Rookie of the Year.

Wood would go on to record over 200 strikeouts in four out of his first five seasons, with a high of 266 in 2003. He holds several MLB strikeout records. Though he struggled with injuries throughout his career, Wood was twice named an All-Star. Wood transitioned to a relief pitcher in 2007 due to continued struggles with injuries, ultimately reviving his career as a closer. During his career Wood was placed on the disabled list 14 times in 14 major league seasons, which included missing the entire 1999 season due to Tommy John surgery. After a slow start to the 2012 season, Wood retired on May 18, 2012.