The first Prime Minister of Pakistan, Liaquat Ali Khan, is assassinated in Rawalpindi.

Liaquat Ali Khan (Urdu: listen ; 1 October 1895 16 October 1951), also referred to in Pakistan as Quaid-e-Millat ( , 'Leader of the Nation') or Shaheed-e-Millat ( , 'Martyr of the Nation'), was a Pakistani statesman, lawyer, political theorist, and one of the leading Pakistan Movement activists. On 15 August 1947, one day after the partition of India, Khan became the first prime minister of Pakistan; he also held cabinet portfolio as the first foreign minister, defence minister, and frontier regions minister from 1947 until his assassination in 1951. Prior to the partition, Khan briefly tenured as the first Indian finance minister in the Interim Government led by Louis Mountbatten, the then-Viceroy of India.He was a democratic political theorist who promoted parliamentarism in British India. After first being invited to the Indian National Congress, he later opted to join the All-India Muslim League led by Muhammad Ali Jinnah, an Indian independence activist who later advocated for a separate Muslim nation-state out of Hindu-majority India; Khan assisted Jinnah in the campaign for what would become known as the Pakistan Movement.

As prime minister of newly independent Pakistan at the beginning of the Cold War, Khan's foreign policy sided with the United States-led Western Bloc over the Soviet Union-led Eastern Bloc, though he was also determined to be a part of the Non-Aligned Movement. Facing internal unrest in Balochistan and discontent for his handling of the First Kashmir War against India, his government survived an attempted coup by left-wing political opponents who were spearheaded by segments of the Pakistani military in 1951. Nevertheless, he remained quite popular among the masses and was responsible for promulgating the Objectives Resolution, which stipulated that the developing Pakistani constitution would not adopt a European ideological pattern, but instead would be fundamentally based on the ideology of Islam. On 16 October 1951, Khan was assassinated by a hired assassin, Said Akbar, at a political rally in the city of Rawalpindi.

The Prime Minister of Pakistan (Urdu: وزِیرِ اعظم پاکستان , lit. 'Grand vizier', Urdu pronunciation: [ʋəˈziːr-ˌeː ˈɑː.zəm]), officially the Prime Minister of the Islamic Republic of Pakistan, is the constitutional head of government of Pakistan and designated as the "Chief Executive of Islamic Republic".

The prime minister leads the executive branch of the government, oversees economic growth, leads the National Assembly, heads the Council of Common Interests as well as the Cabinet, and is vested with the command authority over the nuclear arsenals. This position places its holder in leadership of the nation and in control over all matters of internal and foreign policy. The prime minister is elected by the members of the National Assembly and therefore is usually the leader of the majority party in the parliament. The Constitution of Pakistan vests the executive powers in the prime minister, who is responsible for appointing the Cabinet as well as running the executive branch, taking and authorising executive decisions, appointments and recommendations that require executive confirmation of the prime minister.Constitutionally, the prime minister serves as the chief adviser to the president of Pakistan on critical matters and plays an influential role in appointment in each branch of the military leadership as well as ensuring the control of the military through chairman joint chiefs. Powers of the prime minister have significantly grown with a delicate system of the check and balance by each branch. The position was absent during years of 1960–73, 1977–85 and 1999–2002 due to imposed martial law. In each of these periods, the military junta led by the president had the powers of the prime minister.Imran Khan has held the office of Prime Minister since 18 August 2018, following the outcome of nationwide general elections held on 25 July 2018.He will now face a vote of no confidence from the opposition in the parliament house