The University of Greifswald is established, making it the second oldest university in northern Europe (also for a period the oldest in Sweden, and Prussia).

The University of Greifswald (German pronunciation: [ˈɡʁaɪfsvalt]; German: Universität Greifswald), formerly also known as “Ernst-Moritz-Arndt University of Greifswald“, is a public research university located in Greifswald, Germany, in the state of Mecklenburg-Western Pomerania.

Founded in 1456 (teaching existed since 1436), it is one of the oldest universities in Europe, with generations of notable alumni and staff having studied or worked in Greifswald. As the fourth oldest university in present Germany, it was temporarily also the oldest university of the Kingdoms of Sweden (1648–1815) and Prussia (1815–1945), respectively. Approximately two-thirds of the 10,179 students are from outside the state, including foreign students from 90 countries all over the world. Due to the small-town atmosphere, the pronounced architectural presence of the alma mater across town, and the young, academic flair in the streets, Greifswald is often described as a "university with a town built around it" rather than a town with a university.