A woman (either Margaret Hughes or Anne Marshall) appears on an English public stage for the first time, in the role of Desdemona in a production of Shakespeare's play Othello.

Othello (full title: The Tragedy of Othello, the Moor of Venice) is a tragedy written by William Shakespeare, probably in 1603, set in the contemporary OttomanVenetian War (15701573) fought for the control of the Island of Cyprus, a possession of the Venetian Republic since 1489. The port city of Famagusta finally fell to the Ottomans in 1571 after a protracted siege. The story revolves around two characters, Othello and Iago. Othello is a Moorish military commander who was serving as a general of the Venetian army in defence of Cyprus against invasion by Ottoman Turks. He has recently married Desdemona, a beautiful and wealthy Venetian lady much younger than himself, against the wishes of her father. Iago is Othello's malevolent ensign, who maliciously stokes his master's jealousy until the usually stoic Moor kills his beloved wife in a fit of blind rage. Due to its enduring themes of passion, jealousy, and race, Othello is still topical and popular and is widely performed, with numerous adaptations.

Margaret Hughes (29 May 1630 – 1 October 1719), also Peg Hughes or Margaret Hewes, is often credited as the first professional actress on the English stage, as a result of her appearance on 8 December 1660. Hughes was the mistress of the English Civil War general Prince Rupert of the Rhine.